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Inventi Impact: Med Chem

Articles

  • Inventi:pmc/32720/20
    Synthesis and Characterization of New Series of 1,3-5-Triazine Hydrazone Derivatives with Promising Antiproliferative Activity
    Research 2020 : October - December
    Hessa H Al Rasheed, Azizah M Malebari, Kholood A Dahlous, Ayman El-Faham

    A new series of s-triazine hydrazone derivatives was prepared based on the reaction\nof 6-hydrazino-2,4-disubstituted-s-triazine with p-substituted benzaldehyde derivatives using\na straightforward synthetic pathway. The antiproliferative activity of all synthesized compounds was\nevaluated against two human cancer cell lines; breast cancer MCF-7 and colon carcinoma HCT-116\nusing MTT assay. Among all, 11 compounds have shown strong to moderate antiproliferative activity\nwith IC50 values in the range 1.01â??18.20.................................................................................................

    How to Cite this Article
    Attribution/ CC Compliant Citation: H Al Rasheed, Hessa H. Al, et al. \"Synthesis and Characterization of New Series of 1, 3-5-Triazine Hydrazone Derivatives with Promising Antiproliferative Activity.\" Molecules 25.11 (2020): 2708.\nhttps://doi.org/10.3390/molecules25112708\nhttp://creativecommons.org/licenses/by/4.0/\nSome formatting elements, header, footer, logos, dates and pagination were modified while adapting this article.
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